Agewell topic desk
64 briefsbrain health
Readable reporting on memory, sleep, stress, learning, and the conditions that help a mind stay engaged.
The useful question
What helps the brain stay capable, curious, and well supported?
Program perspective
About the framework Walk the Luminous Mind spiral 📄 Download Companion Field Guide (PDF) In Canada, the supplements for this protocol are stocked at our Fullscript dispensary. Commission-supported; no added cost to you.Published briefs
Source-linked reading
- 01
August 21, 2026 · arXiv q-bio
Beyond Labels: A Continuous Score for Alzheimer’s Progression
- 02
August 21, 2026 · Medical Xpress Healthy Aging
Hormonal tides reshape the brain: MRE reveals estrogen-driven mechanical plasticity in the hippocampus
- 03
August 20, 2026 · Medical Xpress Healthy Aging
Gray and white matter jointly shape cognitive aging, new evidence shows
- 04
August 20, 2026 · bioRxiv neuroscience, genetics, physiology
Alzheimer’s and ageing dismantle the brain’s information topology
- 05
August 19, 2026 · Medical Xpress Healthy Aging
AI brain age gap flags dementia risk years before symptoms
- 06
August 19, 2026 · Medical Xpress Healthy Aging
Vitamin D and the aging brain: a signal worth decoding
- 07
August 18, 2026 · Medical Xpress Neurology
Brain imaging reveals how an information hub integrates signals during decision-making
- 08
August 17, 2026 · Medical Xpress Healthy Aging
Air pollution etches its signature on Alzheimer’s-vulnerable brain regions
- 09
August 17, 2026 · ScienceDaily Healthy Aging
A New Alzheimer’s Target: How a Broken Enzyme Clogs Mitochondria and Drives Dementia
- 10
August 16, 2026 · bioRxiv neuroscience, genetics, physiology
β-Arrestin2: A Sex-Specific Molecular Switch in Alzheimer’s Pathology
- 11
August 15, 2026 · bioRxiv neuroscience, genetics, physiology
Your brain’s plumbing runs on a 24-hour clock: new study links wakefulness and CSF oscillations
- 12
August 14, 2026 · Medical Xpress Healthy Aging
Gut Bacterial Metabolite Raises Alzheimer’s Risk: A New Target for Intervention
- 13
August 14, 2026 · Medical Xpress Neurology
Blood biomarkers for Alzheimer’s: a universal protein signature, but population-specific calibration is critical
- 14
August 14, 2026 · ScienceDaily Healthy Aging
Estrogen-only therapy in later life linked to fewer Alzheimer’s signs in the brain
- 15
August 13, 2026 · Medical Xpress Sleep
Astrocytes: The Sleep Architects Rewiring Memory Circuits
- 16
August 13, 2026 · ScienceDaily Top Health
Exercise primes the brain’s glymphatic system to clear metabolic waste
- 17
August 12, 2026 · Frontiers in Human Neuroscience
Can a Nerve in Your Ear Wake the Unconscious Brain? The Biophysics of taVNS
- 18
August 12, 2026 · bioRxiv neuroscience, genetics, physiology
Your Brain Syncs, Your Body Engages: New EEG Study Dissects Attention from Listening Immersion
- 19
August 12, 2026 · Medical Xpress Healthy Aging
Sleep architecture as an early sentinel for Alzheimer’s risk
- 20
August 11, 2026 · Medical Xpress Neurology
Microglial Waste Clearance: The Shared Cellular Pathway Behind Childhood Dementia and Alzheimer’s
- 21
August 11, 2026 · Medical Xpress Neurology
Senescent microglia secrete a protein that drives brain aging
- 22
August 11, 2026 · eLife Neuroscience
Glial Surface Protein DIP-β Extends Lifespan in Flies: A Molecular Bridge to Brain Aging
- 23
August 9, 2026 · bioRxiv immunology and cell biology
T-cell checkpoints: the immune dial that tunes brain resilience to amyloid
- 24
August 9, 2026 · Medical Xpress Sleep
REM Sleep Turns the Brain Inward: New EEG Evidence of Sensory Gating
- 25
August 8, 2026 · Frontiers in Human Neuroscience
The Locus Coeruleus: A Tiny Brain Nucleus That Orchestrates Cognition and Predicts Neurodegeneration
- 26
August 8, 2026 · Medical Xpress Healthy Aging
Aging brains draft blood-borne immune reinforcements: the blood-brain barrier is not a wall
- 27
August 7, 2026 · ScienceDaily Top Health
Your Brain’s Immune System Is Being Replaced—Starting at 50
- 28
August 6, 2026 · Medical Xpress Neurology
Tau’s mitochondrial sabotage: reversing electron flow in Alzheimer’s
- 29
August 5, 2026 · Neuroscience News
Overall brain health buffered memory against early Alzheimer’s pathology
- 30
August 5, 2026 · Frontiers in Human Neuroscience
Lifelong bilingualism preserved pre-attentive hearing discrimination with age
- 31
August 4, 2026 · Medical Xpress Healthy Aging
An AI model charted how separate brain regions age at different rates
- 32
August 3, 2026 · bioRxiv neuroscience, genetics, physiology
Cerebellar network timing supported episodic memory in older adults
- 33
August 3, 2026 · eLife Neuroscience
Synapses turned over constantly while their excitatory-inhibitory balance held
- 34
August 3, 2026 · SciTechDaily
Disrupted Circadian Rhythms Linked to Elevated Dementia Risk
- 35
August 3, 2026 · eLife Neuroscience
In zebrafish, serotonin neurons induced stillness without dulling the senses
- 36
August 3, 2026 · bioRxiv immunology and cell biology
An experimental flu adjuvant sped early antibody quality in over-60s
- 37
August 3, 2026 · bioRxiv neuroscience, genetics, physiology
In mice, briefly disrupting body-position sense caused navigation errors
- 38
August 3, 2026 · arXiv q-bio
Person-specific brain mapping improved Alzheimer’s detection from fMRI
- 39
August 3, 2026 · arXiv machine learning
Blood tests advanced while many AI cognition tools still await validation
- 40
August 3, 2026 · Spiral of Cellular Light companion guide
The Luminous Mind framework treats brain health as a whole-system project
- 41
August 2, 2026 · ScienceDaily
Weaker daily rhythms carried nearly 2.5 times the dementia risk
- 42
August 2, 2026 · The Guardian | Alternative medicine
A scan of 558 herbal remedy books found 82% likely AI-written
- 43
August 2, 2026 · The Guardian | Alternative medicine
Indigenous voices on the cost of commodified plant medicine
- 44
August 2, 2026 · ScienceDaily Healthy Aging
Patient-derived brain organoids predicted who responded to an antidepressant
- 45
August 2, 2026 · ScienceDaily Healthy Aging
Across 214,000 older adults, dementia risk factors varied by country
- 46
August 2, 2026 · ScienceDaily Healthy Aging
A microglial switch may separate who declines from who stays sharp
- 47
August 2, 2026 · ScienceDaily Healthy Aging
SuperAgers’ memory advantage was not explained by their Alzheimer’s genes
- 48
August 2, 2026 · ScienceDaily Healthy Aging
A brain waste-clearance gene altered how much poor sleep costs
- 49
August 2, 2026 · Medical Xpress Sleep
Three brain regions synchronised during sleep to consolidate memory
- 50
August 2, 2026 · ScienceDaily Healthy Aging
In mice, removing brain immune cells restored two hours of sleep
- 51
August 2, 2026 · Medical Xpress Nutrition
In 47 older women, six months of time-restricted eating aided spatial planning
- 52
August 2, 2026 · ScienceDaily Healthy Aging
APOE2 neurons showed less DNA damage and better repair
- 53
August 2, 2026 · ScienceDaily Healthy Aging
In 1,700 adults, frequent midlife TV tracked smaller memory regions
- 54
August 2, 2026 · NIH News Releases
Researchers map how single neurons assemble spoken language
- 55
August 2, 2026 · Medical Xpress Healthy Aging
Choroid plexus MRI measures tracked later dementia risk
- 56
August 2, 2026 · ScienceDaily Healthy Aging
A sleep EEG ‘brain age’ score tracked future dementia risk
- 57
August 2, 2026 · NIH News Releases
New Blood Test May Predict Alzheimer’s Symptoms Years Ahead
- 58
August 2, 2026 · Medical Xpress Healthy Aging
Work stress tracked persistent sleep problems in 70% of over-50s
- 59
August 2, 2026 · NIH News Releases
Brain’s Immune System Changes at Midlife, NIH Study Finds
- 60
August 2, 2026 · Medical Xpress Sleep
Sleep loss triggered a brain immune response that damaged tissue
- 61
August 2, 2026 · Medical Xpress Sleep
More evidence tied physical activity to lower dementia risk
- 62
August 12, 2025 · PubMed
Ribosome rescue factor Pelota extends lifespan and counters age-related pathology across species
- 63
August 1, 2025 · biorxiv
Memory’s hidden order: uniform sampling, not surprise, shapes what we recall
- 64
August 1, 2025 · biorxiv
Itch and pain split by a single gene switch in spinal neurons