Agewell topic desk
6 briefscellular senescence
A grounded guide to senescence research, healthspan questions, and what remains unsettled about senolytic approaches.
The useful question
What can senescence research tell us, and what is still a hypothesis?
Program perspective
About the framework Walk the Cell Shedding spiral 📄 Download Companion Field Guide (PDF) In Canada, the supplements for this protocol are stocked at our Fullscript dispensary. Commission-supported; no added cost to you.Published briefs
Source-linked reading
- 01
August 3, 2026 · Spiral of Cellular Light companion guide
What the cell-shedding framework gets right about senescence research
- 02
June 18, 2026 · PubMed
FARS-1/FARSA: A tRNA Synthetase That Silences Mitochondrial dsRNAs to Extend Lifespan
- 03
June 18, 2026 · PubMed
Mitochondria hand protons to lysosomes: a new acidification pathway that fails with age
- 04
March 6, 2026 · PubMed
Flavonoid from vine tea selectively clears senescent microglia, repairs DNA in aging cells
- 05
September 1, 2025 · PubMed
Nanomedicine that targets ATP synthase reverses bone aging in mice
- 06
August 1, 2025 · PubMed
Chemical reprogramming extends lifespan in worms, reverses aging hallmarks in human cells